When I saw this article in Annals , I was sure that I have seen it before, but could not believe that 2 studies with almost same methods, same number of patients, and same dose of medication.
First one AJEM , Feb, 2015. Annlas of EM published Subdissociative-Dose Ketamine Versus Morphine for Analgesia. Prospective, randomized, double-blind trial, Ketamine at 0.3 mg/kg or Morphine at 0.1 mg/kg by IV push during 3 to 5 minutes. 45 patients in each group. Ketamine with dose of 0.3 mg/kg provides pain relief and also safe compare to Morphince for acute pain management in ED