Amiodarone with Dose of 300 mg!!!

I was reading an article regarding Managing Afib in Annals of EM. They are recommending Amiodarone 300 mg IV over an hour and then 10-50 mg/hour for 24 hour.

I thought something wrong with this, but I checked their reference and it is correct. So, don’t be surprise of dose of 300 mg in alive patient!

Amiodarone is a very invasive IV medication and I believe we have to use other options before we get to this dose!

2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary