{"id":166,"date":"2011-10-31T14:24:37","date_gmt":"2011-10-31T18:24:37","guid":{"rendered":"http:\/\/emeddoc.org\/?p=166"},"modified":"2011-10-31T15:12:32","modified_gmt":"2011-10-31T19:12:32","slug":"pediatric-uti-practice-guideline-from-aap","status":"publish","type":"post","link":"https:\/\/emeddoc.org\/?p=166","title":{"rendered":"Pediatric UTI; Practice guideline from AAP"},"content":{"rendered":"<p style=\"text-align: justify;\">Recently, AAP published a practice guideline on &#8220;Urinary Tract Infection: Clinical Practice Guideline for the Diagnosis and Management of the Initial UTI in Febrile Infants and Children\u00a0 <!--more-->2 to 24 Months&#8221; in Sept, 2011. There are a lot of useful information about UTI, diagnosis and treatment. You can see the <a href=\"http:\/\/pediatrics.aappublications.org\/content\/128\/3\/595.long\">article here<\/a> but I highlighted some of data:<\/p>\n<p style=\"text-align: justify;\">1. If you apply urine bag and your test(culture) is negative you can count on it but if it is positive due to high false positive you should not interpret the result.<\/p>\n<p style=\"text-align: justify;\">2. Girls with :<\/p>\n<p style=\"text-align: justify;\">A. no identifiable source of infection<\/p>\n<p style=\"text-align: justify;\">B. White Race<\/p>\n<p style=\"text-align: justify;\">C. Age &lt; 12 months<\/p>\n<p style=\"text-align: justify;\">D. Onset of symptoms(&lt;2 days)<\/p>\n<p style=\"text-align: justify;\">E. Fever =&gt;39<\/p>\n<p style=\"text-align: justify;\">=\u00a0 1% probability of UTI for 1 risk factor<\/p>\n<p style=\"text-align: justify;\">= 2% probability of UTI for 2 risk factors<\/p>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/pediatrics.aappublications.org\/content\/128\/3\/595\/F2.large.jpg\">Link to AAP<\/a><\/p>\n<p style=\"text-align: justify;\">3. <a href=\"http:\/\/pediatrics.aappublications.org\/content\/128\/3\/595\/T1.expansion.html\">Sensitivity and Specificity of Components of Urinalysis<\/a><\/p>\n<table id=\"table-1\" frame=\"hsides\">\n<thead id=\"thead-1\">\n<tr id=\"tr-1\">\n<th id=\"th-1\" align=\"center\">Test<\/th>\n<th id=\"th-2\" align=\"center\">Sensitivity (Range), %<\/th>\n<th id=\"th-3\" align=\"center\">Specificity (Range), %<\/th>\n<\/tr>\n<\/thead>\n<tbody id=\"tbody-1\">\n<tr id=\"tr-2\">\n<td id=\"td-1\" align=\"left\">Leukocyte esterase test<\/td>\n<td id=\"td-2\" align=\"char\">83 (67\u201394)<\/td>\n<td id=\"td-3\" align=\"char\">78 (64\u201392)<\/td>\n<\/tr>\n<tr id=\"tr-3\">\n<td id=\"td-4\" align=\"left\">Nitrite test<\/td>\n<td id=\"td-5\" align=\"char\">53 (15\u201382)<\/td>\n<td id=\"td-6\" align=\"char\">98 (90\u2013100)<\/td>\n<\/tr>\n<tr id=\"tr-4\">\n<td id=\"td-7\" align=\"left\">Leukocyte esterase or nitrite test positive<\/td>\n<td id=\"td-8\" align=\"char\">93 (90\u2013100)<\/td>\n<td id=\"td-9\" align=\"char\">72 (58\u201391)<\/td>\n<\/tr>\n<tr id=\"tr-5\">\n<td id=\"td-10\" align=\"left\">Microscopy, WBCs<\/td>\n<td id=\"td-11\" align=\"char\">73 (32\u2013100)<\/td>\n<td id=\"td-12\" align=\"char\">81 (45\u201398)<\/td>\n<\/tr>\n<tr id=\"tr-6\">\n<td id=\"td-13\" align=\"left\">Microscopy, bacteria<\/td>\n<td id=\"td-14\" align=\"char\">81 (16\u201399)<\/td>\n<td id=\"td-15\" align=\"char\">83 (11\u2013100)<\/td>\n<\/tr>\n<tr id=\"tr-7\">\n<td id=\"td-16\" align=\"left\">Leukocyte esterase test, nitrite test, or microscopy positive<\/td>\n<td id=\"td-17\" align=\"char\">99.8 (99\u2013100)<\/td>\n<td id=\"td-18\" align=\"char\">70 (60\u201392)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/pediatrics.aappublications.org\/content\/128\/3\/595\/T1.expansion.html\">Link to Article<\/a><\/p>\n<p style=\"text-align: justify;\">4. Treatment should be for 7-14 days:<\/p>\n<p style=\"text-align: justify;\"><strong>PO antibiotic:<\/strong><\/p>\n<p style=\"text-align: justify;\">&nbsp;<\/p>\n<table id=\"table-3\" frame=\"hsides\">\n<thead id=\"thead-3\">\n<tr id=\"tr-15\">\n<th id=\"th-6\" align=\"center\">Antimicrobial Agent<\/th>\n<th id=\"th-7\" align=\"center\">Dosage<\/th>\n<\/tr>\n<\/thead>\n<tbody id=\"tbody-3\">\n<tr id=\"tr-16\">\n<td id=\"td-31\" align=\"left\">Amoxicillin-clavulanate<\/td>\n<td id=\"td-32\" align=\"left\">20\u201340 mg\/kg per d in 3 doses<\/td>\n<\/tr>\n<tr id=\"tr-17\">\n<td id=\"td-33\" align=\"left\">Sulfonamide<\/td>\n<td id=\"td-34\"><\/td>\n<\/tr>\n<tr id=\"tr-18\">\n<td id=\"td-35\" align=\"left\">Trimethoprim-sulfamethoxazole<\/td>\n<td id=\"td-36\" align=\"left\">6\u201312 mg\/kg trimethoprim and 30-60 mg\/kg sulfamethoxazole per d in 2 doses<\/td>\n<\/tr>\n<tr id=\"tr-19\">\n<td id=\"td-37\" align=\"left\">Sulfisoxazole<\/td>\n<td id=\"td-38\" align=\"left\">120\u2013150 mg\/kg per d in 4 doses<\/td>\n<\/tr>\n<tr id=\"tr-20\">\n<td id=\"td-39\" align=\"left\">Cephalosporin<\/td>\n<td id=\"td-40\"><\/td>\n<\/tr>\n<tr id=\"tr-21\">\n<td id=\"td-41\" align=\"left\">Cefixime<\/td>\n<td id=\"td-42\" align=\"left\">8 mg\/kg per d in 1 dose<\/td>\n<\/tr>\n<tr id=\"tr-22\">\n<td id=\"td-43\" align=\"left\">Cefpodoxime<\/td>\n<td id=\"td-44\" align=\"left\">10 mg\/kg per d in 2 doses<\/td>\n<\/tr>\n<tr id=\"tr-23\">\n<td id=\"td-45\" align=\"left\">Cefprozil<\/td>\n<td id=\"td-46\" align=\"left\">30 mg\/kg per d in 2 doses<\/td>\n<\/tr>\n<tr id=\"tr-24\">\n<td id=\"td-47\" align=\"left\">Cefuroxime axetil<\/td>\n<td id=\"td-48\" align=\"left\">20\u201330 mg\/kg per d in 2 doses<\/td>\n<\/tr>\n<tr id=\"tr-25\">\n<td id=\"td-49\" align=\"left\">Cephalexin<\/td>\n<td id=\"td-50\" align=\"left\">50\u2013100 mg\/kg per d in 4 doses<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\">&nbsp;<\/p>\n<p style=\"text-align: justify;\"><strong>IV Antibiotic:<\/strong><\/p>\n<table id=\"table-2\" frame=\"hsides\">\n<thead id=\"thead-2\">\n<tr id=\"tr-8\">\n<th id=\"th-4\" align=\"center\">Antimicrobial Agent<\/th>\n<th id=\"th-5\" align=\"center\">Dosage<\/th>\n<\/tr>\n<\/thead>\n<tbody id=\"tbody-2\">\n<tr id=\"tr-9\">\n<td id=\"td-19\" align=\"left\">Ceftriaxone<\/td>\n<td id=\"td-20\" align=\"left\">75 mg\/kg, every 24 h<\/td>\n<\/tr>\n<tr id=\"tr-10\">\n<td id=\"td-21\" align=\"left\">Cefotaxime<\/td>\n<td id=\"td-22\" align=\"left\">150 mg\/kg per d, divided every 6\u20138 h<\/td>\n<\/tr>\n<tr id=\"tr-11\">\n<td id=\"td-23\" align=\"left\">Ceftazidime<\/td>\n<td id=\"td-24\" align=\"left\">100\u2013150 mg\/kg per d, divided every 8 h<\/td>\n<\/tr>\n<tr id=\"tr-12\">\n<td id=\"td-25\" align=\"left\">Gentamicin<\/td>\n<td id=\"td-26\" align=\"char\">7.5 mg\/kg per d, divided every 8 h<\/td>\n<\/tr>\n<tr id=\"tr-13\">\n<td id=\"td-27\" align=\"left\">Tobramycin<\/td>\n<td id=\"td-28\" align=\"left\">5 mg\/kg per d, divided every 8 h<\/td>\n<\/tr>\n<tr id=\"tr-14\">\n<td id=\"td-29\" align=\"left\">Piperacillin<\/td>\n<td id=\"td-30\" align=\"left\">300 mg\/kg per d, divided every 6\u20138 h<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\">&nbsp;<\/p>\n<p style=\"text-align: justify;\">all these are from New practice guideline by American Academy of Pediatrics Journal<\/p>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/pediatrics.aappublications.org\/content\/128\/3\/595.long\">Link to article<\/a><\/p>\n<p style=\"text-align: justify;\">&nbsp;<\/p>\n<p style=\"text-align: justify;\">&nbsp;<\/p>\n<p style=\"text-align: justify;\">&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recently, AAP published a practice guideline on &#8220;Urinary Tract Infection: Clinical Practice Guideline for the Diagnosis and Management of the Initial UTI in Febrile Infants and Children\u00a0<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18,13,14,15,16],"tags":[],"class_list":["post-166","post","type-post","status-publish","format-standard","hentry","category-pediatrics","category-pgy1","category-pgy2","category-pgy3","category-pgy4"],"_links":{"self":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=166"}],"version-history":[{"count":7,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/166\/revisions"}],"predecessor-version":[{"id":171,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/166\/revisions\/171"}],"wp:attachment":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=166"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=166"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}