{"id":541,"date":"2014-09-04T12:42:23","date_gmt":"2014-09-04T16:42:23","guid":{"rendered":"http:\/\/emeddoc.org\/?p=541"},"modified":"2014-09-04T12:42:51","modified_gmt":"2014-09-04T16:42:51","slug":"morphine-delays-clopidogrel-effects","status":"publish","type":"post","link":"https:\/\/emeddoc.org\/?p=541","title":{"rendered":"Morphine delays Clopidogrel effects!"},"content":{"rendered":"<p>Morphine can affect functionality of Clopidogrel. There is an article in JACC, March 2014, that showed &#8220;<span class=\"highlight\">Morphine<\/span> delays <span class=\"highlight\">clopidogrel<\/span> absorption, <span class=\"highlight\">decreases<\/span> plasma levels of <span class=\"highlight\">clopidogrel<\/span> active metabolite, and retards and diminishes its <span class=\"highlight\">effects<\/span>, <!--more-->which can lead to treatment failure in susceptible individuals&#8221;. This will bring a problem with patient that the pain is not controlled with Nitro and now the choice of pain meds is&#8230;.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/content.onlinejacc.org\/article.aspx?articleID=1787884\">Link to website<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Morphine can affect functionality of Clopidogrel. There is an article in JACC, March 2014, that showed &#8220;Morphine delays clopidogrel absorption, decreases plasma levels of clopidogrel active metabolite, and retards and diminishes its effects,<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,13,14,15,16],"tags":[],"class_list":["post-541","post","type-post","status-publish","format-standard","hentry","category-cardiology","category-pgy1","category-pgy2","category-pgy3","category-pgy4"],"_links":{"self":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/541","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=541"}],"version-history":[{"count":2,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/541\/revisions"}],"predecessor-version":[{"id":543,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/541\/revisions\/543"}],"wp:attachment":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=541"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=541"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=541"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}