{"id":553,"date":"2014-10-16T11:24:34","date_gmt":"2014-10-16T15:24:34","guid":{"rendered":"http:\/\/emeddoc.org\/?p=553"},"modified":"2014-10-16T11:31:12","modified_gmt":"2014-10-16T15:31:12","slug":"thershold-for-blood-transfusion","status":"publish","type":"post","link":"https:\/\/emeddoc.org\/?p=553","title":{"rendered":"Thershold for Blood Transfusion"},"content":{"rendered":"<p>In my series of EBM, I was talking on our grand rounds regarding restrictive vs liberal strategies for blood transfusion! I have already posted the <a title=\"Blood Transfusion in 2014\" href=\"https:\/\/emeddoc.org\/?p=529\" target=\"_blank\">evidence<\/a> for it. But NEJM published a study in septic shock patient that will really change practice: <!--more--><span style=\"font-size: small;\">This is a multi-center, parallel-group trial, they randomly assigned 998 patients in the ICU who had <b>septic shock<\/b> and they did transfusion when the hemoglobin level was 7 g per deciliter or less (lower threshold) versus when the level was 9 g per deciliter or less (higher threshold) during the ICU stay. The primary outcome measure was death by 90 days after randomization. As other study showed their conclusion is&#8221; patients with septic shock who underwent transfusion at a hemoglobin threshold of 7 g per deciliter, as compared with those who underwent transfusion at a hemoglobin threshold of 9 g per deciliter, received fewer transfusions and had similar mortality at 90 days, use of life support, and number of days alive and out of the hospital; the numbers of patients with ischemic events and severe adverse reactions to blood in the ICU were also similar in the two intervention groups.&#8221;<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1406617\">Link to article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In my series of EBM, I was talking on our grand rounds regarding restrictive vs liberal strategies for blood transfusion! I have already posted the evidence for it. But NEJM published a study in septic shock patient that will really change practice:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28,13,14,15,16],"tags":[],"class_list":["post-553","post","type-post","status-publish","format-standard","hentry","category-hematology","category-pgy1","category-pgy2","category-pgy3","category-pgy4"],"_links":{"self":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/553","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=553"}],"version-history":[{"count":4,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/553\/revisions"}],"predecessor-version":[{"id":557,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/553\/revisions\/557"}],"wp:attachment":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=553"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=553"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=553"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}