{"id":756,"date":"2016-02-29T21:49:19","date_gmt":"2016-03-01T02:49:19","guid":{"rendered":"http:\/\/emeddoc.org\/?p=756"},"modified":"2016-02-29T21:49:19","modified_gmt":"2016-03-01T02:49:19","slug":"gout-and-steroids","status":"publish","type":"post","link":"https:\/\/emeddoc.org\/?p=756","title":{"rendered":"Gout and Steroids!"},"content":{"rendered":"<p><span id=\"ctl00_scm6MainContent_lblClientName\"><em>Annals of Internal Medicine <\/em>published a\u00a0Multicenter, Double-Blind, Randomized Trial and compared Oral Prednisolone in the Treatment of Acute Gout. P<span id=\"ctl00_scm6MainContent_rptSections_ctl23_lblSection\" class=\"Paragraph 117229690 117229689 3\">atients were randomly assigned in a 1:1 ratio to receive either indomethacin or prednisolone for 5 days. <\/span>The regimen was for patients <span id=\"ctl00_scm6MainContent_rptSections_ctl20_lblSection\" class=\"Paragraph 117229687 117229685 3\">presented to the ED within 3 days of symptom onset. <\/span><em><br \/>\n<\/em><\/span><\/p>\n<ol>\n<li><strong>Indomethacin<\/strong> group: <span id=\"ctl00_scm6MainContent_rptSections_ctl25_lblSection\" class=\"Paragraph 117229692 117229689 3\">patients<\/span> received 50 mg (two 25-mg tablets) of the drug three times a day for 2 days, followed by 25 mg of Indomethacin three times a day for 3 days.<\/li>\n<li><span id=\"ctl00_scm6MainContent_rptSections_ctl25_lblSection\" class=\"Paragraph 117229692 117229689 3\"><strong>Prednisolone<\/strong> group: patients initially received 30 mg (three 10-mg tablets) of oral prednisolone once a day for 5 days.<br \/>\n<\/span><\/li>\n<\/ol>\n<p>The conclusion is <span id=\"ctl00_scm6MainContent_rptSections_ctl00_lblSection\" class=\"Abstract 117229665 0 1\">Oral prednisolone and indomethacin had similar analgesic effectiveness among patients with acute gout.<\/span> <span id=\"ctl00_scm6MainContent_rptSections_ctl00_lblSection\" class=\"Abstract 117229665 0 1\">Prednisolone<\/span> could be the first line of treatment in acute gout.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/annals.org\/article.aspx?articleid=2494539\">Link to article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Annals of Internal Medicine published a\u00a0Multicenter, Double-Blind, Randomized Trial and compared Oral Prednisolone in the Treatment of Acute Gout. Patients were randomly assigned in a 1:1 ratio to receive either indomethacin or prednisolone for 5 days. The regimen was for patients presented to the ED within 3 days of symptom onset. Indomethacin group: patients received [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,13,14,15,16],"tags":[],"class_list":["post-756","post","type-post","status-publish","format-standard","hentry","category-orthopedics","category-pgy1","category-pgy2","category-pgy3","category-pgy4"],"_links":{"self":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/756","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=756"}],"version-history":[{"count":2,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/756\/revisions"}],"predecessor-version":[{"id":758,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/756\/revisions\/758"}],"wp:attachment":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}