{"id":855,"date":"2017-06-12T03:16:39","date_gmt":"2017-06-12T07:16:39","guid":{"rendered":"http:\/\/emeddoc.org\/?p=855"},"modified":"2017-06-12T03:16:39","modified_gmt":"2017-06-12T07:16:39","slug":"mono-or-dual-therapy-for-cellulitis","status":"publish","type":"post","link":"https:\/\/emeddoc.org\/?p=855","title":{"rendered":"Mono or Dual Therapy for Cellulitis"},"content":{"rendered":"<p>It is very interesting that how fast we are changing our practice lately. Still remember when we started to give double dose of TMP\/SMZ plus cephalexin for cellulitis, and then we changed it to 1 dose of TMP\/SMZ + cephalexin and then we doubted if cephalexin is necessary or not. JAMA published a randomized study showing &#8220;Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis&#8221;.\u00a0 496 patients received cephalexin plus trimethoprim-sulfamethoxazole vs cephalexin plus placebo in uncomplicated cellulitis. They found no difference in higher rates of clinical resolution of cellulitis, only slightly different in treating diabetic and adverse effect!<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/jamanetwork.com.proxygw.wrlc.org\/journals\/jama\/fullarticle\/2627970\">Link to article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It is very interesting that how fast we are changing our practice lately. Still remember when we started to give double dose of TMP\/SMZ plus cephalexin for cellulitis, and then we changed it to 1 dose of TMP\/SMZ + cephalexin and then we doubted if cephalexin is necessary or not. JAMA published a randomized study [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,13,14,15,16],"tags":[],"class_list":["post-855","post","type-post","status-publish","format-standard","hentry","category-diabetes","category-pgy1","category-pgy2","category-pgy3","category-pgy4"],"_links":{"self":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/855","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=855"}],"version-history":[{"count":1,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/855\/revisions"}],"predecessor-version":[{"id":856,"href":"https:\/\/emeddoc.org\/index.php?rest_route=\/wp\/v2\/posts\/855\/revisions\/856"}],"wp:attachment":[{"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=855"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=855"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/emeddoc.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=855"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}