Azithromycin received considerable attention during the COVID-19 pandemic for its potential antiviral and anti-inflammatory effects and is also commonly used for coverage of atypical respiratory infections. At the same time, increasing antimicrobial resistance has raised questions about when its use is most appropriate. A recent NEJM study evaluated whether azithromycin could reduce the severity of […]
Continue ReadingThe link below provides the “Recommendations for Prevention and Control of Influenza in Children, 2025–2026” policy statement. I will leave it to your discretion to determine how you would like to incorporate this into the practice guidelines. Link to article
Continue ReadingIn cases of hyperemesis gravidarum, our initial approach typically involves administering glucose-containing solutions to address ketosis. A recent study published in Pediatric Emergency Care demonstrated that, in the pediatric population, higher intravenous glucose administration was associated with a reduced risk of hospitalization and lower rates of return visits. Link to article
Continue ReadingIn a recent article published in the British Journal of Surgery, Jain et al. conducted a multicenter superiority randomized controlled trial (RCT) involving 451 children with nail bed injuries. The study showed that, following nail bed repair, discarding the fingernail yielded similar rates of infection and cosmetics ratings as replacing the fingernail Link to article
Continue ReadingA recent study by Savage et al., utilizing propensity score matching, revealed that children under 17 years of age diagnosed with acute sinusitis demonstrated no significant difference in the rate of treatment failure between those receiving amoxicillin and those receiving augmentin. However, it is worth noting that the latter group had a higher risk of […]
Continue ReadingLevetiracetam versus phenytoin? Which one do you use in case of status epilepticus in children? A multicentre, open-label, randomised trial publishe by the Lancet suggests that levetiracetam could be an alternative “as the first-choice, second-line anticonvulsant in the treatment of paediatric convulsive status epilepticus.” Link to article
Continue ReadingAnother great PECARN study: Headache in Traumatic Brain Injuries From Blunt Head Trauma published in Pediatrics, Feb 2015.
Continue ReadingJuly 2012: Annals of Emergency Medicine: Early Administration of Systemic Corticosteroids Reduces
Continue ReadingThis is a retrospective cohort study between 2004-2007 among patients who received a treatment with clindamycin, trimethoprim-sulfamethoxazole, or a β-lactam for their skin and soft-tissue infections.
Continue ReadingI thought I posted this before but I did not, Pediatrcis 2011, prospective cohort study with 2574 patients under 21 years old. Interestingly, 16 % of patients had radiographic pneumonia.
Continue ReadingKocher Criteria is the best way to diagnose septic arthritis in children
Continue ReadingIs a lumbar puncture necessary when evaluating febrile infants (30 to 90 days of age) with an abnormal urinalysis? There is a new study in Peds Emergency care which it describes a retrospective study among infants 1 month to 3 months old
Continue ReadingIdentification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. The goal of study was to identify children at very low risk of clinically-important traumatic brain injuries (ciTBI) for whom CT might be unnecessary.
Continue ReadingRecently, AAP published a practice guideline on “Urinary Tract Infection: Clinical Practice Guideline for the Diagnosis and Management of the Initial UTI in Febrile Infants and Children
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