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Category: Hematology

DOAC versus LMWH in patient with CANCER

August 20, 2023August 20, 2023Pourmand

LMWH traditionally was recommended for venous thromboembolism (VTE) treatment in cancer patient. Recent JAMA article that enrolled 671 patients between 2016 and 2020 found DOACs are non inferior to LMWH for preventing recurrent VTE over 6-month follow-up . Link to article

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Blood Transfusion Threshold!

October 17, 2016Pourmand

I think everyone is practicing based on Hb&Hct threshold. We have great studies show Hb of 7 could be the trigger point to start for blood transfusion. The latest publication from JAMA showed that we are in a right direction in our practice.   Link to article

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Thershold for Blood Transfusion

October 16, 2014October 16, 2014Pourmand

In my series of EBM, I was talking on our grand rounds regarding restrictive vs liberal strategies for blood transfusion! I have already posted the evidence for it. But NEJM published a study in septic shock patient that will really change practice:

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Sickle Cell Disease

September 9, 2014Pourmand

I was giving lecture regarding this topic and some challenging concepts in SCC including  IV therapy, oxygen therapy, blood transfusion, and always could not give a comprehensive reference to back myself up.

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Blood Transfusion in 2014

July 22, 2014July 22, 2014Pourmand

I had several discussions in ED regarding blood transfusion in anemic patients. My argument is that if patient does not have any acute symptoms (SOB, feeling faint, tachycardia, Cardiac ischemia, …), there is no need to emergently

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Complications Associated with Sickle Cell Trait

June 24, 2012June 24, 2012Pourmand

We usually believe that pt with sickle cell trait is not as important as SCD(HbSS). In sickle cell trait, RBC has normal life span (120 vs 20) and no vaso-oclusive crisis. But article in the American Journal of Medicine, discussed a series of serious complication that can affect this type of patient ranging from hematuria, […]

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