Amoxi or Amoxi-Clavulanate for Acute Sinusitis?
When considering oral broad-spectrum antibiotic therapy for acute sinusitis, clinicians often favor amoxicillin-clavulanate over amoxicillin alone. However, a large retrospective cohort study published in JAMA evaluated 521,244 adult patients diagnosed with acute sinusitis, of whom 65.5% were female, and found that amoxicillin alone was not associated with higher rates of treatment failure compared with amoxicillin-clavulanate. […]
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