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Category: Seizure

First Time Seizure in the ED

July 26, 2023July 26, 2023Pourmand

This is an observational study among patients presenting to 3 EDs with Seizure and they found approximately 12 % of patients had some neuroimaging findings! Link to the article

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Seizure Therapy if Benzo fails!

November 29, 2019November 29, 2019Pourmand

We know the first approach to seizure usually is benzodiazepines after ABC, but in status epiliepticus we should start another agent to control patient’s seizure activity that does not stop or have a breakthrough. NEJM in a RCT of 3 AED reported that levetiracetam, fosphenytoin, and valproate each: could stop seizure activity in half of […]

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EBM, on unprovoked first seizure from Neurology!

August 12, 2015August 12, 2015Pourmand

Evidence-based guideline: Management of an unprovoked first seizure in adults: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society answers  very critical questions regarding unprovoked first seizure.

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Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus

March 1, 2012Pourmand

This study is interesting because Maryland EMS has a protocol to give Midazolam IM in prehospital setting. The New England journal published on Feb,16, 2012 a double-blind, randomized study comparing IM Midazolam versus IV Lorazepam for children and adults in status epilepticus.

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