Morphine delays Clopidogrel effects!

Cardiology PGY1 PGY2 PGY3 PGY4

Morphine can affect functionality of Clopidogrel. There is an article in JACC, March 2014, that showed “Morphine delays clopidogrel absorption, decreases plasma levels of clopidogrel active metabolite, and retards and diminishes its effects, which can lead to treatment failure in susceptible individuals”. This will bring a problem with patient that the pain is not controlled with Nitro and now the choice of pain meds is….


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