Whole Blood in Traumatic Hemorrhage

A recent randomized controlled trial published in the New England Journal of Medicine compared prehospital transfusion of whole blood in trauma setting with separate administration of red blood cells and plasma (two units each) to evaluate whether whole blood reduces mortality. The study found that whole blood transfusion was not superior to component therapy in […]

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High-Flow Oxygen in Hypoxemic Respiratory Failure

There is a growing body of literature evaluating the role of high-flow nasal oxygen in acute hypoxemic respiratory failure, particularly in comparison with standard oxygen therapy and noninvasive ventilation. Based on my own clinical experience, high-flow oxygen may offer improved patient tolerance and comfort compared with noninvasive ventilation. A recent randomized, multicenter, open-label trial published […]

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